{"id":635,"date":"2016-02-12T13:42:00","date_gmt":"2016-02-12T13:42:00","guid":{"rendered":"http:\/\/www.papatyafunda.com\/?p=635"},"modified":"2020-09-24T23:28:52","modified_gmt":"2020-09-24T23:28:52","slug":"tipta-nobellik-bulus","status":"publish","type":"post","link":"https:\/\/www.papatyafunda.com\/?p=635","title":{"rendered":"T\u0131pta nobellik bulu\u015f"},"content":{"rendered":"\n

VATANDA\u015e \u0130\u00c7\u0130N \u00c7ALI\u015eAN CESUR Y\u00dcREKTEN ASRIN BULU\u015eU, 2.NOBEL \u00d6D\u00dcL\u00dc KAPIDA!<\/p>\n\n\n\n

\u0130nsano\u011flu do\u011far, b\u00fcy\u00fcr ve \u00e7e\u015fitli sebeplerden \u00f6l\u00fcr. Bu \u00f6l\u00fcm sebebi enfakt\u00fcs olabilir, kanser, trafik kazas\u0131 vs olabilir ama g\u00fcn\u00fcm\u00fczde \u00f6l\u00fcmlerin %55-60\u2019\u0131 damar sertli\u011finden oluyor.  \u2018\u0130nsano\u011flu atardamar\u0131 kadar ya\u015f\u0131yor.\u2019 Diyor Kardiyoloji , Kalp ve Damar Hastal\u0131klar\u0131 uzman\u0131 Prof. Dr. Faruk Erzengin, \u00fclkemize 2.Nobel \u00f6d\u00fcl\u00fc kazand\u0131rabilecek de\u011ferde bir bulu\u015f ile T\u0131p D\u00fcnyas\u0131na ad\u0131n\u0131 alt\u0131n harflerle yazd\u0131rd\u0131. Haz\u0131rlad\u0131\u011f\u0131 ila\u00e7 gruplar\u0131yla damar i\u00e7i sertli\u011fini s\u00f6k\u00fcp at\u0131yor, ayr\u0131ca bir\u00e7ok kronik hastal\u0131\u011fa da deva oluyor. \u00d6nce Vatan Gazetesi olarak, t\u00fcm insanl\u0131\u011fa bu haberi ilk kez duyurabilmenin hakl\u0131 gururunu ya\u015f\u0131yoruz.<\/p>\n\n\n\n

Prof. Dr. Faruk Erzengin hocam, insan olarak \u00e7ok donan\u0131ml\u0131, y\u0131llarca kendini geli\u015ftiren, s\u00fcrekli yeti\u015ftiren azimli, y\u00fcre\u011fi \u00f6nce Allah sevgisi, \u00dclkemiz, Halk\u0131m\u0131z ve sonra da insanl\u0131\u011f\u0131n iyili\u011fi i\u00e7in \u00e7arpan, gece g\u00fcnd\u00fcz insanl\u0131\u011fa fayda i\u00e7in \u00e7al\u0131\u015fan, az uyuyup \u00e7ok, \u00e7ok \u00e7al\u0131\u015fan( Faruk Hocam buna; \u201c \u00d6rne\u011fin y\u00fcz ya\u015fasak gece ge\u00e7er ellisi, uyursak bo\u015fa gider bu \u00f6mr\u00fcn bellisi\u201d diyor), 2 d\u00f6nem \u00fcst \u00fcste \u0130.\u00dc. \u0130stanbul (\u00c7apa) T\u0131p Fak\u00fcltesinde se\u00e7imle kazanarak Fak\u00fcltesi tarihinde en gen\u00e7 ve en y\u00fcksek oy alarak maksimum s\u0131n\u0131r olan  toplam 6 y\u0131l Dekanl\u0131k yapan \u00e7ok \u00f6zel bir insan. Ben ba\u015fta olmak \u00fczere, y\u00fczlerce, binlerce insan\u0131n hayat\u0131n\u0131 kurtaran, t\u00fcm halk\u0131m\u0131z ve d\u00fcnya taraf\u0131ndan \u00e7ok iyi bilinen m\u00fckemmel bir insand\u0131r, O\u2019nu tan\u0131mak \u015fans\u0131m\u0131zd\u0131r. \u00d6nce Allah\u2019a sonra da Prof. Dr. Faruk ERZENG\u0130N\u2019 e kendimizi emanet ediyoruz.<\/p>\n\n\n\n

500\u2019\u00fcn \u00fczerinde yay\u0131n\u0131 olan bilim adam\u0131<\/p>\n\n\n\n

Damar sertli\u011fi ve tedavisinde bilinenlerin \u00f6tesine ge\u00e7erek ezber bozan T\u00fcrk doktorlar, y\u0131llard\u0131r y\u00fcr\u00fctt\u00fckleri bilimsel \u00e7al\u0131\u015fmalarla t\u0131p literat\u00fcr\u00fcne girecek \u00f6nemli bir ba\u015far\u0131ya imza att\u0131lar. Kardiyoloji ve Kalp Damar Cerrahisinden Patolojiye, Endokrinolojiden Genetik\u2019e kadar 32 profes\u00f6r\u00fcn yer ald\u0131\u011f\u0131 ekibin ba\u015f\u0131nda \u0130stanbul T\u0131p Fak\u00fcltesi eski Dekan\u0131 ve Kardiyoloji Ana Bilim Dal\u0131 en k\u0131demli hocas\u0131 Prof. Dr. Faruk Erzengin bulunuyor. Daha \u00f6nce \u00c7apa Kamp\u00fcs\u00fc\u2019nde  6 y\u0131l (iki d\u00f6nem) se\u00e7imle kazanarak Dekanl\u0131k g\u00f6revi de yapan Prof. Dr. Erzengin; y\u00fcr\u00fctt\u00fckleri \u00e7al\u0131\u015fman\u0131n sadece T\u00fcrkiye i\u00e7in de\u011fil, t\u00fcm d\u00fcnya ve insanl\u0131k i\u00e7in \u00e7ok m\u00fchim oldu\u011funun alt\u0131n\u0131 \u00e7izerek, \u201c\u0130nsanlar  bir\u00e7ok sebepten dolay\u0131 \u00f6l\u00fcyor. Bu nedenler aras\u0131nda Kalp ve Damar Hastal\u0131klar\u0131, Damar sertli\u011fine ba\u011fl\u0131 t\u00fcm hastal\u0131klar (\u00f6rne\u011fin inmeler gibi) ba\u015f\u0131 \u00e7ekiyor. \u00d6ne \u00e7\u0131kan bu sebepleri ara\u015ft\u0131rd\u0131\u011f\u0131m\u0131zda insano\u011flunun ya\u015fam\u0131nda atar damar\u0131n\u0131n \u00f6mr\u00fcn\u00fcn \u00e7ok \u00f6nemli oldu\u011fu ger\u00e7e\u011fiyle kar\u015f\u0131la\u015f\u0131yoruz. Hatta \u201c\u0130nsan, atar damarlar\u0131 kadar ya\u015f\u0131yor\u201d diyebiliriz. \u00c7\u00fcnk\u00fc beyine giden damar t\u0131kand\u0131\u011f\u0131nda insan fel\u00e7 ge\u00e7irebilir, sakat kal\u0131r veya \u00f6l\u00fcr. Kalbe giden atar damar t\u0131kand\u0131\u011f\u0131nda enfakt\u00fcs ya\u015fan\u0131r. Baca\u011fa giden atar damar t\u0131kand\u0131\u011f\u0131nda ise kangren ortaya \u00e7\u0131kar. \u00d6zetle ya\u015fam\u0131m\u0131zda atar damarlar \u00e7ok \u00f6nemlidir ve insano\u011flu atar damar\u0131 kadar ya\u015fayabiliyor. Bizler; 32 ki\u015fiden olu\u015fan \u00c7al\u0131\u015fma Grubu\u2019muz ile damar sertli\u011fi ve tedavileri anlam\u0131nda \u00f6zg\u00fcn bir \u00e7al\u0131\u015fma yaparak, klasik bilgilerin \u00f6tesine ge\u00e7meyi ba\u015fard\u0131k\u201d \u015feklinde a\u00e7\u0131klamada bulunuyor.<\/p>\n\n\n\n

DAMAR SERTL\u0130\u011e\u0130NDE EZBER BOZULDU!<\/p>\n\n\n\n

Damar sertli\u011finin, atar damarlar\u0131n (arterlerin) \u00fczerinde hangi b\u00f6lgelerde ortaya \u00e7\u0131kt\u0131\u011f\u0131 ve tedavi i\u00e7in \u00e7\u00f6z\u00fcm yollar\u0131yla ilgili sofistike ara\u015ft\u0131rmalar yapt\u0131klar\u0131n\u0131, b\u00f6ylece klasik bilgilere ek olarak  baz\u0131 \u015fa\u015f\u0131rt\u0131c\u0131 ger\u00e7eklere ula\u015ft\u0131klar\u0131n\u0131 belirten Prof. Dr. Faruk Erzengin a\u00e7\u0131klamas\u0131n\u0131 \u015f\u00f6yle s\u00fcrd\u00fcr\u00fcyor: \u201cAtar damarlarda \u00fc\u00e7 tabaka bulunuyor. \u00dcst (d\u0131\u015f) k\u0131sm\u0131na Adventisya, orta tabakaya Media, en i\u00e7 tabakaya ise \u0130ntima diyoruz. Birde bu \u00fc\u00e7 tabakay\u0131 birbirinden ay\u0131ran iki elastik yap\u0131 var (Lamina elastika eksterna ve interna). Klasik olarak eskiden \u015fu biliniyordu; damar sertli\u011fi yapan lipitler, oksi LDL ve 250 den fazla etkenler damara \u0130ntimal tabakadan,  yani damar\u0131n en i\u00e7 \u00f6rt\u00fcs\u00fc olan ve tek tek h\u00fccrelerin s\u0131ralanmas\u0131ndan olu\u015fan Endotel’den girer ve \u0130ntimal tabakaya oturur ve burada birikirler, Lipid plaklar\u0131n\u0131 olu\u015ftururlar. Bu lipid (ya\u011f) olu\u015fumlar\u0131, \u00f6nce biraz damar\u0131n d\u0131\u015f\u0131na do\u011fru b\u00fcy\u00fcme g\u00f6sterse de (remodeling=yeniden \u015fekillenme), sonra damar\u0131n i\u00e7ine do\u011fru b\u00fcy\u00fcme yapar. B\u00f6ylece plaklar olu\u015farak damar\u0131n i\u00e7i daral\u0131r. Bu plaklar\u0131n \u00fczeri bir tabaka ile kapl\u0131 olup baz\u0131 plaklarda incedir ve  bunlara hassas (Vulnerable) plak denir. Plak \u00e7o\u011fu zamamn  omuz k\u0131sm\u0131  denilen b\u00f6lgeden, ya da \u00fcst\u00fcn\u00fc kaplayan kaps\u00fcl\u00fcn en ince yerinden \u00e7atlayarak i\u00e7indeki lipitkoru ve komponenti damar\u0131n i\u00e7ine do\u011fru bo\u015fal\u0131r. Bu esnada koruyucu fakt\u00f6rler, ba\u015fta trombusler gelir bunun etraf\u0131nda toplan\u0131r ve burada t\u0131ka\u00e7 olu\u015fturur. Neticede damarda i\u00e7ten t\u0131kan\u0131kl\u0131k veya darl\u0131k meydana gelir. Olu\u015fan damar t\u0131kan\u0131kl\u0131\u011f\u0131 bazen kan ak\u0131m\u0131n\u0131n tam durmas\u0131na sebep olur, bazen de k\u0131smen gitmesini engeller. T\u0131pta bu duruma \u201cdamar\u0131n i\u00e7ten t\u0131kanmas\u0131\u201d deniyor. Damar sertli\u011finin, Media tabakas\u0131nda olu\u015ftu\u011fu zaten daha evvelce ispatl\u0131yd\u0131. Biz ise; damar\u0131n her tabakas\u0131nda bu i\u015fin olabilece\u011fini ortaya \u00e7\u0131kard\u0131k. \u00c7al\u0131\u015fma Grubumuz ile yapt\u0131\u011f\u0131m\u0131z incelemelerde; koroner arter aterosklerozunda plak olu\u015fumu ve kalsifik tutulum, klasik intimal kaskad yolu d\u0131\u015f\u0131nda yani yaln\u0131z endotel h\u00fccreleri alt\u0131ndan de\u011fil, adventisya tabakas\u0131ndan da ba\u015flayabilece\u011fini ve ilerleyebilece\u011fini ve damar\u0131n l\u00fcmeninde (i\u00e7inde) daralmaya, t\u0131kanmaya sebep olabilece\u011fini ortaya koyduk.\u201d<\/p>\n\n\n\n

\u0130LA\u00c7 TEDAV\u0130S\u0130 \u00d6L\u00dcMDEN KURTARACAK<\/p>\n\n\n\n

Damar t\u0131kan\u0131kl\u0131\u011f\u0131n\u0131n sadece endotel h\u00fccreleri alt\u0131nda (\u0130ntima) veya M\u00f6nckeberg\u2019in tariff etti\u011fi arterin orta tabakas\u0131 olan Muskuler Media tabakas\u0131nda olabildi\u011fi gibi, atardamar\u0131n (arterin) en d\u0131\u015f tabakas\u0131 olan Adventisya dan da ba\u015flayabilece\u011fini d\u00fcnyada ilk kez tespit etmekle kalmad\u0131klar\u0131n\u0131 belirten Prof. Dr. Erzengin, damar t\u0131kan\u0131kl\u0131\u011f\u0131yla ilgili d\u00fcnyada ilk olan te\u015fhisin yan\u0131nda, devaml\u0131 ilerleyen bu hastal\u011fa ekibiyle birlikte ila\u00e7la \u00e7\u00f6z\u00fcm ve tedavi y\u00f6ntemleri de geli\u015ftirdiklerini ifade ediyor ve \u015f\u00f6yle diyor: \u201cGayemiz sadece damar t\u0131kan\u0131kl\u0131\u011f\u0131yla ilgili yeni te\u015fhisler ortaya koymak de\u011fildir.<\/p>\n\n\n\n

Bu hastal\u0131k, y\u0131llard\u0131r durdurulamaz ve hatta geriletilemez olarak bilinirdi, biz bu hastal\u0131\u011fa kar\u015f\u0131 y\u0131llard\u0131r yaln\u0131z ila\u00e7la \u00e7\u00f6z\u00fcm ve medikal tedavi y\u00f6ntemleri \u00fczerinde de \u00e7al\u0131\u015ft\u0131k ve \u00e7ok belirgin ba\u015far\u0131lar elde ettik. \u00d6zetle aterosklerozun (dammar sertli\u011finin) durdurulabildi\u011fini ve tamamen geriletebildi\u011fini ortaya koyduk. Uzun zamand\u0131r DETEA ve benzeri ileri tetkik ve deney laboratuvarlar\u0131m\u0131zda atelostolozun tiperini, sebeplerini, olu\u015f nedenlerini ve olu\u015f mekanizmalar\u0131n\u0131 ara\u015ft\u0131rd\u0131k.<\/p>\n\n\n\n

Hastal\u0131\u011f\u0131n y\u00fczde 60 kadar\u0131 klasik intima yoluyla ger\u00e7ekle\u015fiyor ama M\u00f6nkemek\u2019in tarif etti\u011fi skreloz y\u00fczde 3 kadar bir oranda damar sertli\u011fini olu\u015fturuyor. Bize g\u00f6re dammar sertli\u011finin (aterosklerozun) geri kalan y\u00fczde 35-40 kadar\u0131 Adventisyadan ba\u015fl\u0131yor. Bu da ya kalbin etraf\u0131ndaki epikardial ya\u011f tabakas\u0131ndan kom\u015fuluk yoluyla (diffuzyon yoluyla) veya atardamarlar\u0131 besleyen arterioller, yani incecik k\u0131lcal arterlarle (vasevasorum denilen, atar damar\u0131n kendisini besleyen temiz kan\u0131 getiren k\u0131lcal atar damarlar yoluyla)  tekrar belirteyim klasik kaskaddaki endotelden giren 250 den fazla fakt\u00f6rlerin,bu ikinci de\u011fi\u015fik bir yol olan arterin d\u0131\u015f tabakas\u0131na ula\u015fmas\u0131yla olu\u015fuyor.<\/p>\n\n\n\n

NOBEL\u2019E ADAY OLAB\u0130LECEK B\u0130R \u00c7ALI\u015eMA<\/p>\n\n\n\n

Bilimsel \u00e7al\u0131\u015fmalar\u0131ndaki hedefi; \u201cdamar sertli\u011fini \u00f6nlemek ve bu hastal\u0131k nedeniyle daha \u00f6nce by pas amaliyet\u0131 oldu\u011fu halde, hastal\u0131\u011f\u0131 devam edenlerin rahats\u0131zl\u0131\u011f\u0131n\u0131 tamamen ortadan kald\u0131rmak\u201d \u015feklinde \u00f6zetleyen Prof. Dr. Erzengin, \u00e7arp\u0131c\u0131 sonu\u00e7lar\u0131 olan \u00e7al\u0131\u015fmalar\u0131na dair g\u00f6r\u00fc\u015flerini \u015fu s\u00f6zlerle anlat\u0131yor: \u201cS\u00fcrekli ilerleyen bir process olan ve ciddi \u00f6ld\u00fcr\u00fcc\u00fc sonu\u00e7lara yol a\u00e7an bu arterleri tutan damar sertli\u011finin, yaln\u0131z ila\u00e7lar yoluyla tedavisini bulmay\u0131 ama\u00e7lad\u0131k. Nitekim ba\u015f\u0131nda bulundu\u011fum 32 ki\u015filik \u00c7al\u0131\u015fma Grubu, d\u00fcnya \u00e7ap\u0131nda ses getirecek bu \u00f6nemli ba\u015far\u0131ya imza att\u0131. Kimya M\u00fchendisli\u011finden Patolojiye, Genetikten Allerjiye pek\u00e7ok bran\u015ftaki profes\u00f6rlerin olu\u015fturdu\u011fu \u00e7al\u0131\u015fma grubumuzda; Kardiyoloji ve Kalp Damar Cerrahisinden, Patoloji ve Diyabetolojiye, SEM kalsiyum-Lipid tarama ve haritalama incelemesinden fizyopotolojiye kadar, hatta kimya m\u00fchendislerine kadar bir\u00e7ok uzman yer ald\u0131. \u0130dealimiz deneysel ve klinik temele dayanan bu \u00e7al\u0131\u015fmam\u0131z\u0131n Nobel \u00d6d\u00fcl\u00fc\u2019ne aday olabilmesidir. Bana g\u00f6re \u00fcniversite ve bilim kurumlar\u0131n\u0131n en \u00f6nemli hedefi; \u00fcretti\u011fi \u00e7al\u0131\u015fma ve projelerle nobele aday olabilecek i\u015flere imza atmas\u0131d\u0131r.\u201d<\/p>\n\n\n\n

D\u00dcNYA \u00c7APINDA B\u0130R DE\u011eER<\/p>\n\n\n\n

Peki Prof. Dr. Faruk Erzengin kimdir? Bu sorunun yan\u0131t\u0131 i\u00e7in y\u0131llar \u00f6ncesine gitmeliyiz. \u0130\u015fte bug\u00fcn T\u00fcrkiye i\u00e7in \u00e7ok \u00f6nemli bir bilim adam\u0131 olan Prof. Dr. Erzengin\u2019in d\u00fcnden, bug\u00fcne uzanan ya\u015fam \u00f6yk\u00fcs\u00fcn\u00fcn sat\u0131rba\u015flar\u0131\u2026 T\u00fcrkiye Cumhuriyeti tarihinin En Gen\u00e7 Dekan\u2019\u0131 (se\u00e7imle gelen, tarihteki en y\u00fcksek oyu alan ve maksimum yap\u0131labilen iki d\u00f6nemi ya\u015fayarak toplam 6 y\u0131l g\u00f6rev yapan) \u00fcnvan\u0131n\u0131 elinde tutan Prof. Dr. Faruk Erzengin\u2019in \u00e7al\u0131\u015fmalar\u0131, d\u00fcnyan\u0131n bir\u00e7ok \u00fclkesinde yak\u0131ndan izleniyor. Doppler-Renkli Doppler Ekokardiyografi ve Trans\u00f6zofajiyal Eko- kardiyografiyi \u00fclkemize ilk getiren (Avrupadan da \u00f6nce \u00fclkemizde kuran ve sonar da \u0130ngiltere\u2019de kuran bilim adam\u0131 olan Prof. Dr. Erzengin, T\u00fcrk Kardiyoloji Derne\u011fi Yeterlilik ve Etik Kurulu Ba\u015fkan\u0131\u2026 4 Y\u0131l S\u00fcrekli E\u011fitim Komisyonu Ba\u015fkanl\u0131\u011f\u0131 yapan, Avrupa ve T\u00fcrkiye Kardiyoloji \u00c7ekirdek E\u011fitim M\u00fcfredat\u0131 (ESC Core Curriculum)T\u00fcrkiye Sorumlusu ve Ba\u015fkan\u0131 olarak \u00e7al\u0131\u015fan ve Avrupa Kardiyoloji Derne\u011fi T\u00fcrkiye temsilcisi olan Prof. Dr. Erzengin,  \u0130.\u00dc. \u0130stanbul T\u0131p Fak\u00fcltesi’nde, Ba\u015f Hekimlik, E\u011fitim Komisyon Baikanl\u0131\u011f\u0131,1997-1998 y\u0131llar\u0131 aras\u0131nda Sat\u0131nalma Ko- misyon Ba\u015fkanl\u0131\u011f\u0131, D\u00f6ner Sermaye \u0130\u015fletme M\u00fcd\u00fcrl\u00fc\u011f\u00fc ve Tahakkuk Amirli\u011fi yapt\u0131. Ayr\u0131ca 1998 -2004 y\u0131llar\u0131 aras\u0131nda \u0130stanbul T\u0131p Fak\u00fcltesi\u2019nin 2 d\u00f6nem se\u00e7imle gelerek dekanl\u0131\u011f\u0131n\u0131 yapt\u0131.<\/p>\n\n\n\n

B\u0130YOGRAF\u0130S\u0130: 1950 y\u0131l\u0131nda Kahramanmara\u015f\u2019ta 7 \u00e7ocuklu bir ailenin son \u00e7ocu\u011fu olarak d\u00fcnyaya geldi. Babas\u0131; Mara\u015f Kurtulu\u015f Sava\u015f\u0131nda \u00e7ok b\u00fcy\u00fck fedak\u00e2rl\u0131klar g\u00f6steren ve gazi olan Hac\u0131 Mehmet Erzengin\u2019dir ve \u00e7ok k\u00f6kl\u00fc bir ailenin mensubu olup me\u015fhur Hoca ve M\u00fcderris \u00d6mer Efendinin torunudur. Annesi Emine Erzengin, Mara\u015f M\u00fcft\u00fcs\u00fc Me\u015fhur Haf\u0131z Ali Efendi\u2019nin ye\u011fenidir. Muhafazak\u00e2r bir ailenin evlad\u0131 olarak d\u00fcnyaya gelen Faruk Erzengin; \u00fc\u00e7 ya\u015f\u0131ndan itibaren \u00f6nce annesi ve ablalar\u0131n\u0131n ve daha sonraki y\u0131llarda Mara\u015f\u2019\u0131n Fatma Hoca, G\u00f6v\u015fen Haf\u0131z, G\u00fcll\u00fc Hoca, Salih Hoca gibi \u00e7ok \u00fcnl\u00fc din adamlar\u0131n\u0131n verdi\u011fi din\u00ee e\u011fitimle Kuran-\u0131 Kerim\u2019i \u00f6nce hatme\u015fmi\u015f ve devam\u0131nda h\u0131fzetmi\u015f ve 17 ya\u015f\u0131na kadar Haf\u0131z Ali Efendi ba\u015fta olmak \u00fczere pek \u00e7ok \u00fcnl\u00fc hocalar\u0131n rahleyi tedrisinden ge\u00e7erek Osmanl\u0131ca \u00f6\u011frenmi\u015ftir. \u0130lkokulu \u0130stikl\u00e2l \u0130lk Okulu\u2019nda, Orta Okul ve Liseyi Kahramanmara\u015f Lisesinde okumu\u015f ve bu okullar\u0131 birincilikle bitirdi.  \u0130stanbul \u00dcniversitesi \u0130stanbul T\u0131p Fak\u00fcltesi\u2019ne 1966 y\u0131l\u0131nda girdi ve 1972\u2019de derece ile mezun oldu. \u015eubat 1974\u2019e kadar askerlik g\u00f6revini Samsun ve Amasya\u2019da, Eryata\u011f\u0131-Carcurum\u2019da (toplam 18 ay) Tabip Aste\u011fmen olarak yapt\u0131. Mart 1974\u2019te a\u00e7\u0131lan s\u0131navda birinci oldu ve \u0130stanbul T\u0131p Fak\u00fcltesi \u0130\u00e7 Hastal\u0131klar\u0131 K\u00fcrs\u00fcs\u00fc\u2019ndeki asistanl\u0131k g\u00f6revine ba\u015flad\u0131. Daha sonar \u201c\u0130\u00e7 Hastal\u0131klar\u0131 Uzmanl\u0131k\u201d s\u0131nav\u0131n\u0131 \u00fcst\u00fcn derece ba\u015far\u0131 ile kazanarak 1978 y\u0131l\u0131nda Kardiyoloji Anabilim Dal\u0131\u2019nda Ba\u015fasistan olarak \u00e7al\u0131\u015fmaya ba\u015flad\u0131.<\/p>\n\n\n\n

A\u00e7\u0131lan bir s\u0131nav\u0131 kazanarak, \u0130stanbul \u00dcniversitesi taraf\u0131ndan \u201cbilgi ve g\u00f6rg\u00fcs\u00fcn\u00fc artt\u0131rmak\u201d amac\u0131 ile resmi g\u00f6revli olarak 1982 y\u0131l\u0131nda \u0130ngiltere\u2019nin St. James\u2019s \u00dcniversitesi\u2019nce sa\u011flanan \u201cSenior Registrar-Research Fellow\u201d kadrosu ile ayn\u0131 \u00dcniversite\u2019nin T\u0131p Fak\u00fcltesi Kardiyoloji (Kalp ve Damar Hastal\u0131klar\u0131)  Departman\u0131\u2019na g\u00f6nderildi. Ayn\u0131 Kardiyoloji K\u00fcrs\u00fcs\u00fcnde bir\u00e7ok bilimsel \u00e7al\u0131\u015fmalar yapt\u0131 ve Klinik Kardiyolojide ve Kardiyolojinin invazif ve non-invasif t\u00fcm Laboratuarlar\u0131nda \u00e7al\u0131\u015ft\u0131. Anjiyo,  Eko-Doppler ve intraoperatif mukayaselli \u00e7ok ba\u015far\u0131l\u0131 bir\u00e7ok \u00e7al\u0131\u015fmalar ve uluslararas\u0131 yay\u0131nlar ve tebli\u011fler yapt\u0131. \u0130ngilterede a\u00e7\u0131lan bir s\u0131nav\u0131 kazanarak \u201cDoppler\u201d  Ekokardiografiyi ilerletmek ve renkli Doppler Ekokardiyografi\u2019yi \u00f6\u011frenmek ve bu sistemleri ilk olarak \u0130ngiltere\u2019de kurmak \u00fczere St. James\u2019s \u00dcniversitesi taraf\u0131ndan 30.11.1982 tarihinde resmi kadrolu olarak Amerika Birle\u015fik Devletleri Washington ve Seatle \u00dcniversite\u2019lerine, Los Angeles \u00dcniversitesine ve takiben de Cleveland Clinic\u2019e 4 ay s\u00fcre ile g\u00f6nderildi. \u0130ngiltere\u2019ye tekrar d\u00f6nd\u00fckten sonra bu \u00fclkede ilk Doppler Ekokardiografi Laboratuvar\u0131n\u0131 kurdu. \u0130ngiltere\u2019de 2 y\u0131l kald\u0131ktan sonra 31.12.1983 tarihinde \u0130stanbul T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131\u2019na d\u00f6nd\u00fc. \u0130stanbul T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131\u2019n\u0131n, Ekokardiyografi laboratuar\u0131n\u0131n modern ve verimli hale getirilmesi i\u00e7in Ba\u015fkan yard\u0131mc\u0131s\u0131 olarak g\u00f6revlendirildi. Doppler Ekokardiyografi\u2019yi, T\u00fcrkiye\u2019ye ilk getiren ve \u00fclkemizde ilk kez \u0130stanbul \u00dcniversitesi \u0130stanbul T\u0131p Fak\u00fclte\u2019si Kardiyoloji Anabilim Dal\u0131nda\u2019da kuran ki\u015fidir. 1984 y\u0131l\u0131nda Genel Kurul tara- f\u0131ndan, T\u00fcrk Kardiyoloji Derne\u011finin Ekokardiografi \u00c7al\u0131\u015fma Grubu Genel Sekreterli\u011fine se\u00e7ildi. Bu g\u00f6revi 10 y\u0131l y\u00fcr\u00fctt\u00fc\u011f\u00fc d\u00f6nem i\u00e7erisinde Uluslararas\u0131 kat\u0131l\u0131ml\u0131 d\u00f6rt b\u00fcy\u00fck, iki k\u00fc\u00e7\u00fck Ulusal Ekokardiyografi Kongrelerin\u2019in Genel Sekreterli\u011fini ve ba\u015f sorumlulu\u011funu yapt\u0131. Bu arada ayn\u0131 klinikte 1987 y\u0131l\u0131nda Do\u00e7ent oldu.<\/p>\n\n\n\n

\u0130stanbul \u00dcniversitesi, \u0130stanbul T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131 taraf\u0131ndan 1991 y\u0131l\u0131nda Amerika Birle\u015fik Devletleri St. Thomas (Virgin Islands), Miami, Orlando ve Tapma \u015eehirlerinde uygulamal\u0131 Trans\u00f6zofajiyal Ekokardiografi Kursu ve Sempozyumuna ve devam\u0131nda Saint Petersburg \u015eehrindeki Gulfcoast Ultrasound Institute (Florida, USA)\u2019 de, \u201cCardiac Doppler-Color Flow\u201d ve \u201cAdvanced Cadiac Dop-pler\/Color Flow Imaging\u201d ve Trans\u00f6zofajiyal Ekokardiyografi konulu uygu- lamal\u0131 e\u011fitim programlar\u0131na 4 ay s\u00fcre ile resm\u00ee g\u00f6revli olarak g\u00f6nderildi. Fak\u00fcltesine d\u00f6n\u00fc\u015fte Trans\u00f6zofajiyal Ekokardiografi Laboratuvar\u0131n\u0131 \u00dclkemizde ilk defa kurmu\u015f ve bu \u00f6nemli y\u00f6ntemi ilk defa rutin uygulamaya soktu.<\/p>\n\n\n\n

G\u00f6sterdi\u011fi \u00fcst\u00fcn hizmet ve ba\u015far\u0131l\u0131 \u00e7al\u0131\u015fmalar\u0131 takiben, \u00dclkemizdeki farkl\u0131 \u00fcniversitelerden be\u015f farkl\u0131 Profes\u00f6rden olu\u015fan j\u00fcrinin haz\u0131rlad\u0131\u011f\u0131 raporlar\u0131n sonucunda oy birli\u011fi ile ba\u015far\u0131l\u0131 bulunup, \u0130.\u00dc. nin Y\u00f6netim Kurulu\u2019nun oybirli\u011fi karar\u0131 ile1995 y\u0131l\u0131nda aktif Profes\u00f6r oldu. Takip eden y\u0131llarda, Amerika Birle\u015fik Devletleri ve Avrupa\u2019n\u0131n baz\u0131 \u00dcniversitelerinde k\u0131sa, orta ve uzun vadeli \u00e7ok say\u0131da uygulamal\u0131 ve teorik kurs, kongre, konferanslara kat\u0131ld\u0131, tebli\u011flerde bulundu.<\/p>\n\n\n\n

257\u2019si yabanc\u0131 dilde olmak \u00fczere toplam 498 adet makale, ara\u015ft\u0131rma, konferans, derleme \u015feklinde yay\u0131n\u0131 ve \u00fc\u00e7\u00fc yabanc\u0131 dilde olmak \u00fczere alt\u0131 kitapta yazd\u0131\u011f\u0131 konular oldu. Kardiyoloji, Ekokardiyografi, \u0130\u00e7 Hastal\u0131klar\u0131 ve Hipertansiyonla ilgili yaz\u0131lmakta olan d\u00f6rt kitab\u0131n ikisinde edit\u00f6r, ikisinde edit\u00f6r yard\u0131mc\u0131s\u0131d\u0131r. Eyl\u00fcl 2007 de bas\u0131lan 3000 sayfal\u0131k \u0130\u00e7 Hastal\u0131klar\u0131 Kitab\u0131nda Kardiyoloji ile ilgili 14 b\u00f6l\u00fcm  yazm\u0131\u015ft\u0131r ve ayn\u0131 kitab\u0131n Edit\u00f6r Yard\u0131mc\u0131s\u0131d\u0131ri Yeni Kardiyoloji Kitab\u0131nda da baz\u0131 b\u00f6l\u00fcmler yazd\u0131.<\/p>\n\n\n\n

T\u00fcrk T\u0131p Derne\u011fi, T\u00fcrk Kardiyoloji Derne\u011fi, Avrupa Kardiyoloji Derne\u011fi – Fellow of the European Society of Cardiology (FESC) – \u00fcyesi ve ayr\u0131ca Avrupa, Amerika Birle\u015fik Devletleri Ekokardiyografi Derneklerinin \u00fcyesidir. Fenerbah\u00e7e Spor Kul\u00fcb\u00fc Kongre \u00dcyesi ve TED\u2019in \u00fcyesi, Beykoz Spor Kul\u00fcb\u00fcn\u00fcn Ba\u015fkan Yard\u0131mc\u0131s\u0131d\u0131r. Kahraman Mara\u015f Okutma ve Yard\u0131mla\u015fma Derne\u011fi\u2019nin son 14 y\u0131ldan beri Onursal Ba\u015fkan\u0131 olup t\u00fcm hizmetlerde aktif g\u00f6rev al\u0131yor.<\/p>\n\n\n\n

Ocak 1998 tarihinde D\u00f6ner Sermaye \u0130\u015fletme M\u00fcd\u00fcrl\u00fc\u011f\u00fc, Sat\u0131n Alma Komisyon Ba\u015fkanl\u0131\u011f\u0131 ve Tahakkuk Amirli\u011fi g\u00f6revini bir y\u0131l s\u00fcre ile yapt\u0131.<\/p>\n\n\n\n

\u00dcniversitemizi \u0130.\u00dc.Senatosunun ald\u0131\u011f\u0131 kararla; Ankara\u2019da temsilen 2 Ocak 1999 \u2013 4 Ekim 2004 tarihleri aras\u0131nda Y\u00fcksek \u00d6\u011fretim Kurulu \u00dcniversiteler Aras\u0131 Kurul Ba\u015fkanl\u0131\u011f\u0131, Do\u00e7entlik Temel Alan Dan\u0131\u015fma Komisyonu \u00dcyesi olarak aktif g\u00f6rev yapt\u0131 ve bu alanda defalarca Ankara\u2019da Y\u00d6K\u2019te yap\u0131lan komisyon toplant\u0131lar\u0131na resmi g\u00f6revli olarak kat\u0131ld\u0131.<\/p>\n\n\n\n

Ayr\u0131ca son 5 y\u0131ld\u0131r T\u00fcrk Kardiyoloji Derne\u011fi Aday Belirleme Komisyonu \u00fcyesi olarak g\u00f6rev yapt\u0131. 2004\u2019te T\u00fcrk Kardiyoloji Derne\u011fi Genel Kurulu taraf\u0131ndan Yeterlilik \u201cBoard\u201d Kurulu (TKYK) Ba\u015fkan\u0131 se\u00e7ildi. Bu Kurul\u2019un \u00e7ok \u00f6nemli bir e\u011fitim g\u00f6revi olan iki a\u015famal\u0131 Board s\u0131navlar\u0131n\u0131 Kardiyolojide \u00dclkemizde ilk kez ba\u015flatt\u0131. 2012 de T\u00fcrk Kardiyoloji Derne\u011fi Etik Kurul Ba\u015fkanl\u0131\u011f\u0131na se\u00e7ildi, halen bu Komisyon\u2019un ba\u015fkan\u0131 olarak g\u00f6revini s\u00fcrd\u00fcr\u00fcyor.        <\/p>\n\n\n\n

Avrupa Kardiyoloji Derne\u011fi (European Society of Cardiology) taraf\u0131ndan Kardiyoloji \u00c7ekirdek E\u011fitim M\u00fcfredat\u0131  (ESC Core Curriculum) T\u00fcrkiye Sorumlusu ve Ba\u015fkan\u0131 olarak se\u00e7ildi ve 2007\u2019de T\u00fcrkiye\u2019yi temsilen tek sorumlu ve Ba\u015fkan olarak ESC taraf\u0131ndan Parise davet edildi. Avrupa ve T\u00fcrkiye Kardiyoloji \u00c7ekirdek E\u011fitim M\u00fcfredat\u0131 ve Programlar\u0131\u2019n\u0131n toplant\u0131s\u0131nda g\u00f6revli olarak bulundu ve alt \u00c7al\u0131\u015fma Gruplar\u0131n\u0131n ve S\u00fcrekli E\u011fitimin t\u00fcm fonksiyonlar\u0131n\u0131n Avrupa ve \u00dclkemizde haz\u0131rl- anmas\u0131nda ve y\u00fcr\u00fct\u00fclmesinde g\u00f6revlendirildi. Bu g\u00f6revini halen s\u00fcrd\u00fcr\u00fcyor.<\/p>\n\n\n\n

A\u011fustos 1998 ve Eyl\u00fcl 2001  y\u0131llar\u0131nda yap\u0131lan Dekanl\u0131k se\u00e7imlerini tarihteki en y\u00fcksek oy alarak kazand\u0131 ve arka arkaya 2 d\u00f6nem (toplam 6 y\u0131l) \u0130stanbul T\u0131p Fak\u00fcltesi Dekanl\u0131k g\u00f6revini ba\u015far\u0131yla s\u00fcrd\u00fcrd\u00fc. Almanya M\u00fcnih \u00dcniversitesi Rekt\u00f6r\u00fc taraf\u0131ndan Erich FRANK \u00dcst\u00fcn Hizmet Madalyas\u0131 ve Berat\u2019\u0131na lay\u0131k g\u00f6r\u00fcld\u00fc. Ayr\u0131ca bu g\u00f6revi d\u00f6neminde \u00fcst\u00fcn ba\u015far\u0131lar\u0131ndan dolay\u0131 pek \u00e7ok kurum taraf\u0131ndan Profes\u00f6r Dr. Erzengin\u2019e, 50\u2019nin \u00fczerinde \u00f6d\u00fcl ve madalya verildi.<\/p>\n\n\n\n

T\u00fcrk Kardiyoloji Derne\u011fi Etik Kurul Ba\u015fkan\u0131 olan Prof. Dr. Erzengin, T\u00fcrk Kardiyoloji Yeterlilik Kurulunun Kurucu Ba\u015fkan\u0131d\u0131r. \u00dclkemizde ilk olan bu kurumun 4 y\u0131l ba\u015fkanl\u0131\u011f\u0131n\u0131 ba\u015far\u0131yla s\u00fcrd\u00fcrd\u00fc, bin civar\u0131nda Kardiyolog Doktorun s\u0131nav\u0131n\u0131 yaparak Yeterlilik Belgelerini verdi\u011fi i\u00e7in 23 Ekim 2009 da, 25. Ulusal Kardiyoloji Kongresinde, Cumhurba\u015fkan\u0131 Abdulllah G\u00fcl, taraf\u0131ndan \u201c\u00dcst\u00fcn Hizmet \u00d6d\u00fcl\u00fc\u201dne lak\u0131y g\u00f6r\u00fcld\u00fc. Normal Dekanl\u0131k s\u00fcrelerinin bitimini takiben, 7 Eyl\u00fcl 2004 tarihinde, toplam 6 y\u0131ll\u0131k iki d\u00f6nem Dekanl\u0131k s\u00fcresinin tamamlanmas\u0131 nedeni ile tekrar Kardiyoloji Anabilim Dal\u0131ndaki \u00d6\u011fretim \u00dcyeli\u011fi g\u00f6revine d\u00f6nd\u00fc ve h\u00e2len bu g\u00f6reve devam ediyor. \u0130.\u00dc. 2005 y\u0131l\u0131 Rekt\u00f6rl\u00fck se\u00e7iminde 8 aday i\u00e7erisinden ikinci olarak se\u00e7ildi. Erzengin, evli ve 3 \u00e7ocuk babas\u0131d\u0131r.<\/p>\n\n\n\n